Albendazole Oral Suspension
Product Description: Albendazole is being used to treat lymphatic filariasis as part of efforts to stop transmission of intestinal worm diseases. In sub-Saharan Africa, albendazole is used in conjunction with ivermectin, and elsewhere in the world, the medicine is used in combination with diethylcarbamazine.
As a vermicidal, albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies.
Albendazole has larvicidal effects in necatoriasis and ovicidal effects in ascariasis, ancylostomiasis, and trichuriasis.
Product Packaging – The dosages available for this product are:
Albendazole Oral Suspension 2.5%
Albendazole Oral Suspension 10%
Albendazole Oral Suspension can be packaged as 100ml/vial, 120ml/vial, 250ml/vial, 500ml/vial, 1 Liter per bottle, or as per customer requirement.